Guo-Yuan Yang Selected Research

Edema (Dropsy)

8/2023	M2 Microglial Extracellular Vesicles Attenuated Blood-brain Barrier Disruption via MiR-23a-5p in Cerebral Ischemic Mice.
9/2022	Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice.
1/2020	Oligodendrocyte precursor cells transplantation protects blood-brain barrier in a mouse model of brain ischemia via Wnt/β-catenin signaling.
1/2020	P2Y6 receptor inhibition aggravates ischemic brain injury by reducing microglial phagocytosis.
1/2020	MicroRNA-126-3p/-5p Overexpression Attenuates Blood-Brain Barrier Disruption in a Mouse Model of Middle Cerebral Artery Occlusion.
12/2015	MicroRNA-29b is a therapeutic target in cerebral ischemia associated with aquaporin 4.
7/2013	The protective role of Tongxinluo on blood-brain barrier after ischemia-reperfusion brain injury.

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Guo-Yuan Yang Research Topics

Disease

60	Ischemic Stroke 01/2024 - 04/2008
46	Brain Ischemia (Cerebral Ischemia) 01/2023 - 09/2003
42	Stroke (Strokes) 01/2024 - 04/2008
36	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 10/2023 - 05/2002
35	Ischemia 01/2023 - 05/2002
28	Infarction (Infarctions) 01/2024 - 09/2003
28	Brain Injuries (Brain Injury) 01/2024 - 09/2003
14	Brain Infarction 08/2023 - 03/2012
14	Arteriovenous Malformations (Arteriovenous Malformation) 09/2017 - 04/2003
10	Atrophy 01/2024 - 04/2010
9	Inflammation (Inflammations) 02/2024 - 04/2004
9	Hypoxia (Hypoxemia) 11/2017 - 04/2004
8	Brain Edema (Cerebral Edema) 01/2020 - 12/2011
7	Hemorrhage 01/2024 - 05/2005
7	Edema (Dropsy) 08/2023 - 07/2013
7	Cerebral Hemorrhage 01/2020 - 09/2007
7	Aneurysm (Aneurysms) 01/2018 - 06/2008
5	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2023 - 12/2011
5	Brain Diseases (Brain Disorder) 09/2022 - 01/2006
5	Vascular Diseases (Vascular Disease) 11/2017 - 08/2004
5	Neoplasms (Cancer) 01/2017 - 01/2003
4	Thrombosis (Thrombus) 09/2016 - 06/2008
3	Hemorrhagic Stroke 02/2024 - 01/2011
3	Neuroinflammatory Diseases 06/2022 - 09/2018
3	Hypertension (High Blood Pressure) 12/2018 - 09/2006
3	Cerebral Infarction 01/2018 - 04/2008
3	Intracranial Aneurysm (Cerebral Aneurysm) 01/2018 - 06/2008
3	Hereditary Hemorrhagic Telangiectasia 09/2010 - 02/2004
3	Vascular Remodeling 07/2009 - 03/2007
3	Rupture 03/2009 - 09/2007
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 03/2009
2	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 12/2013
2	Pathologic Constriction (Stenosis) 02/2020 - 06/2008
2	Reperfusion Injury 10/2019 - 01/2018
2	Gliosis 10/2018 - 01/2017
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 05/2018 - 01/2016
2	Cognitive Dysfunction 01/2018 - 03/2010

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 11/2023 - 05/2002
15	MicroRNAs (MicroRNA)IBA 06/2022 - 01/2011
13	Interleukin-6 (Interleukin 6)IBA 01/2020 - 01/2006
12	Biomarkers (Surrogate Marker)IBA 01/2019 - 03/2009
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2024 - 02/2004
10	CytokinesIBA 01/2020 - 01/2004
8	Immunoglobulin G (IgG)IBA 08/2023 - 01/2013
7	erucylphosphocholineIBA 01/2023 - 04/2010
6	Matrix Metalloproteinase 9 (Gelatinase B)IBA 09/2022 - 09/2006
6	Netrin-1IBA 12/2021 - 03/2011
6	Matrix Metalloproteinases (MMPs)IBA 12/2011 - 04/2003
5	Evans Blue (Blue, Evans)FDA Link 11/2023 - 12/2011
5	OccludinIBA 11/2023 - 01/2013
5	Therapeutic UsesIBA 01/2023 - 01/2018
5	Neuroprotective AgentsIBA 09/2022 - 11/2017
5	Messenger RNA (mRNA)IBA 07/2019 - 01/2004
5	Caspase 3 (Caspase-3)IBA 05/2009 - 05/2002
4	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 01/2006
4	Oxygen (Dioxygen)IBA 11/2023 - 01/2006
4	Interleukin-10 (Interleukin 10)IBA 10/2023 - 01/2015
4	Tight Junction ProteinsIBA 01/2020 - 11/2017
4	methylarginyl- lysyl- prolyl- tryptophyl- tert- leucyl- leucyl- ethyl esterIBA 01/2016 - 03/2011
3	VimentinIBA 02/2024 - 10/2018
3	Chemokine CXCL12IBA 01/2024 - 08/2009
3	Peptides (Polypeptides)IBA 11/2023 - 05/2022
3	Peroxidase (Myeloperoxidase)IBA 01/2020 - 06/2008
3	Sirolimus (Rapamycin)FDA Link 01/2019 - 02/2014
3	Aquaporin 4IBA 12/2018 - 12/2015
3	Insulin-Like Growth Factor I (IGF-1)IBA 01/2018 - 04/2008
3	Bromodeoxyuridine (BrdU)IBA 01/2017 - 10/2015
3	Interleukin-8 (Interleukin 8)IBA 10/2014 - 01/2013
3	EndoglinIBA 09/2010 - 02/2004
3	Activin Receptors (Activin Receptor)IBA 03/2009 - 02/2004
2	Complement C3 (C3 Complement)IBA 02/2024 - 12/2020
2	HMGB1 Protein (HMG1)IBA 01/2024 - 10/2014
2	cresyl violetIBA 01/2024 - 10/2006
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 11/2023 - 03/2009
2	Metalloproteases (Metalloproteinases)IBA 10/2023 - 04/2003
2	Claudin-5IBA 08/2023 - 12/2021
2	HydrogelsIBA 01/2023 - 11/2022
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2022 - 03/2009
2	Erythropoietin FDA Link 01/2022 - 01/2016
2	Myelin Basic ProteinIBA 01/2022 - 10/2015
2	CateninsIBA 01/2022 - 01/2020
2	Phosphotransferases (Kinase)IBA 12/2021 - 09/2010
2	Mitogen-Activated Protein Kinase 3IBA 01/2021 - 05/2002
2	p38 Mitogen-Activated Protein KinasesIBA 09/2020 - 12/2016
2	CalciumIBA 05/2020 - 04/2007
2	EnzymesIBA 01/2020 - 09/2003
2	Streptozocin (Streptozotocin)FDA Link 01/2020 - 04/2016
2	Tissue Plasminogen Activator (Alteplase)FDA Link 12/2019 - 01/2016
2	3-n-butylphthalide (butylphthalide)IBA 10/2019 - 01/2019
2	Hemoglobins (Hemoglobin)IBA 12/2017 - 11/2017
2	AdiponectinIBA 11/2017 - 12/2013

Therapy/Procedure

47	Therapeutics 01/2024 - 11/2004
24	Transplantation 01/2024 - 08/2005
9	Synchrotrons 12/2019 - 01/2012
7	Sutures (Suture) 09/2017 - 05/2009
5	Lasers (Laser) 01/2019 - 01/2011
3	Suture Techniques 04/2014 - 03/2012
2	Aftercare (After-Treatment) 01/2024 - 11/2017
2	Neurological Rehabilitation 10/2023 - 02/2021
2	Intravenous Injections 01/2022 - 01/2021